Meet EPINOME™
THE PREMIER SUPPLEMENT FORMULA DESIGNED TO TARGET EPIGENETIC SUPPORT AND OPTIMIZE METHYLATION
After four years of Holistic Health—a range through which Clinique La Prairie pioneered the “longevity supplements” segment—we are introducing the fifth pillar of our nutraceutical offering, marking a new pinnacle in nutritional science innovation.
Turn Your Genes into Allies for a Longer, Healthier Life
Introducing EPINOME™, the newest addition to our Clinique La Prairie Holistic Health’s supplement line. Designed to support cellular health, gene regulation and longevity, EPINOME™ harnesses the power of epigenetics—a cutting-edge field that explores how lifestyle and nutrition can influence the way our genes work.
More than three years in the making and backed by the Swiss epigenetics laboratory Genknowme, EPINOME™ is an ultra-targeted supplement engineered to modulate your epigenetic signatures.
But First, Let Us Guide You Through Epigenetics
Epigenetics—literally “on top of” genetics—explores how external factors like lifestyle, diet, and environment influence how our genes function. Rather than changing our genetic code, epigenetics regulates which genes are switched on or off, playing a vital role in key processes like immune response, energy production, and cell renewal.
A central process in epigenetics is methylation, where chemical markers attach to DNA, turning genes on or off. Over time, these methylation patterns can become disrupted, contributing to speeding up aging and increasing cellular dysfunction.
While our genetic code remains fixed, epigenetics is dynamic—meaning we can influence how our genes express themselves and, in turn, how we age. In fact, this process is reversible, allowing us to influence the modulation of our epigenetic signature and potentially alter the course of aging. The environment we live in—and every aspect of our lifestyle—can have an epigenetic impact, from exercise and smoking to alcohol consumption and, of course, nutrition.
Now, You’re Probably Wondering: How Does EPINOME™ Work?
Certain phytochemicals, minerals, and vitamins can act on the chemical markers of DNA—or the proteins surrounding it—through the process explained above: methylation. This is where the EPINOME™ formula began. By addressing epigenetic changes—one of the 12 key mechanisms of aging—EPINOME™ works at the molecular level, harnessing the power of plant-based compounds and targeted nutrients to help restore healthy methylation patterns, particularly those linked to immune strength and inflammation control, and thus support:
Cellular repair and the reduction of stress mechanisms
Healthy, resilient cellular function
Attenuation of inflammatory and oxidative processes at the DNA level
By aligning with your body’s natural biological processes, EPINOME™ offers a new, science-backed nutritional approach to supporting longevity and optimizing health outcomes. Like all Holistic Health products, it delivers real solutions—where therapeutic dosage is a priority, from lab bench to final formula—a level of efficacy that is difficult to achieve through diet alone.
Simone Gibertoni, CEO of Clinique La Prairie and co-founder of HOLISTIC HEALTH, says:
“We are marking another groundbreaking leap in nutraceutical science. This isn’t just the fifth addition to the Holistic Health line; it’s a continuation of our legacy of pioneering new frontiers in at-home longevity solutions.”
Let’s Dive into the Formulation and High-Targeted Ingredients
The formulation of EPINOME™ builds on cutting-edge epigenetic research to combine seven power-packed targeted plant extracts and next generation ingredients with the proprietary CLP Holistic Complex.
Each new ingredient is carefully chosen for its epigenetic relevance, with targeted dosages and proven efficacy. These compounds are not only backed by research but also reflect Clinique La Prairie’s five years of clinical experience in applying epigenetic insights to enhance healthspan.
Discover the seven new ingredients, each connected to a key active component:
Folate L-5-MTHF: The bioactive form of folate. It is studied as essential for methylation processes and gene regulation; it functions as a direct methyl donor (to give scientific context: the methylation of a silenced gene is happening through the addition of a methyl group to the DNA base cytosine).
Cucurbitacin B: Supports cellular pathways linked to growth regulation and oxidative stress, promoting balanced gene expression.
Betulinic Acid: Known for its anti-inflammatory, antiviral and antibacterial properties, it may influence gene activity by reducing inflammation-related proteins.
Ursolic Acid: Helps reduce inflammation and cellular stress, acting as a protective agent to support cellular equilibrium.
Sulforaphane: Studied for its detoxification properties and role in regulating methylation by enhancing antioxidant responses.
Glycyrrhetic Acid: Supports the inhibition of harmful cellular mechanisms, bolsters immune function and defends against oxidative stress.
Coenzyme Q10 (Ubiquinone): Known to enhance mitochondrial energy production, supporting both physical and cognitive performance and maintaining a healthy cellular environment.
Each of these ingredients is delivered through highly expert methods, ensuring both potency and therapeutic efficacy. A sophisticated, science-driven formula of 12 ingredients: seven new actives are synergistically blended with the exclusive Holistic Complex—a fusion of Ashwagandha, Fisetin, Astaxanthin, L-Theanine, and Immucell Beta-Glucans—at the core of each of our longevity supplements.
Olga Donica, Director of Innovation at Clinique La Prairie, says:
“Rooted in years of hands-on work and clinical insights, this is not simply a supplement—it’s a transformative solution dedicated to restoring your healthy epigenetic core. This formula was created to amplify the body’s ability for cellular repair, resilience, and renewal. Inspired by nature and driven by precision, Epinome is a new frontier in longevity, crafted to deliver a profound, lasting impact.”
A Legacy of Epigenetic Expertise
Clinique La Prairie has long been at the forefront of epigenetic science. In 2021, it was the first longevity-focused clinic worldwide to integrate epigenetic testing into its programmes, in collaboration with Swiss laboratory Genknowme — offering personalised insights into how lifestyle factors influence biological aging. Over the past five years, this practice has deepened the clinic’s expertise in epigenetic biology, leading to the development of high-impact lifestyle intervention protocols designed to modulate epigenetic signatures. This knowledge directly informed the creation of EPINOME™. By combining decades of health expertise with advancements in DNA science, EPINOME™ offers another innovative solution in the field of longevity nutraceuticals.
Dr. Semira Gonseth Nusslé, CEO of Genknowme, says:
“Research increasingly demonstrates that nutritional interventions are uniquely positioned to drive long-term improvements in DNA stability and the biological mechanisms of aging. Specific nutrients can influence pathways that impact the methylation of genes crucial for managing inflammation and cellular processes. This is where Holistic Health’s targeted Epinome formula excels. At Genknowme, we are proud to support it and confidently assert that it is backed by our epigenetic testing expertise.”
A New, Crucial Step in Your Daily Routine
EPINOME™ empowers you to act on one of the fundamental drivers of aging. Along with a mindful lifestyle, it gives your body complementary tools to help protect cellular integrity, support healthy gene expression, and unlock your longevity potential.
Getting started is simple: dissolve one sachet in water or juice and enjoy it each morning during or after breakfast.
Designed as a one-month course, EPINOME™ has been formulated as an intermittent nutraceutical solution, allowing for activation and natural reset between cycles—ready to be repeated for long-term impact after a two-month pause.
Pre-Order is Open Now
Here’s our exclusive offer for the launch—secure your EPINOME™ during the May pre-order period. Every pre-order includes an Essential Blend Starter Kit to make your new ritual even more enjoyable. Delivery will follow in June.
Our team at holistic.health@cliniquelaprairie.com is available for all questions you may have.